| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0125 | DvMF_0346 | DvMF_0125 | DvMF_0346 | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | 0.927 |
| DvMF_0125 | DvMF_2185 | DvMF_0125 | DvMF_2185 | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | PFAM: ThiJ/PfpI domain protein; KEGG: bbr:BB3066 hypothetical protein. | 0.502 |
| DvMF_0125 | ispDF | DvMF_0125 | DvMF_0257 | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.556 |
| DvMF_0125 | ispE | DvMF_0125 | DvMF_0486 | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.447 |
| DvMF_0125 | ispH | DvMF_0125 | DvMF_2020 | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.942 |
| DvMF_0346 | DvMF_0125 | DvMF_0346 | DvMF_0125 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| DvMF_0346 | DvMF_0347 | DvMF_0346 | DvMF_0347 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: dde:Dde_1990 SSU ribosomal protein S18P alanine acetyltransferase. | 0.582 |
| DvMF_0346 | DvMF_2185 | DvMF_0346 | DvMF_2185 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | PFAM: ThiJ/PfpI domain protein; KEGG: bbr:BB3066 hypothetical protein. | 0.499 |
| DvMF_0346 | DvMF_2291 | DvMF_0346 | DvMF_2291 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | PFAM: phosphoesterase PA-phosphatase related; KEGG: dde:Dde_0373 phosphoesterase, PA-phosphatase related. | 0.480 |
| DvMF_0346 | ispDF | DvMF_0346 | DvMF_0257 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.465 |
| DvMF_0346 | ispE | DvMF_0346 | DvMF_0486 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.448 |
| DvMF_0346 | ispH | DvMF_0346 | DvMF_2020 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.933 |
| DvMF_0346 | panC | DvMF_0346 | DvMF_2942 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.532 |
| DvMF_0346 | tpiA | DvMF_0346 | DvMF_0348 | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.428 |
| DvMF_0347 | DvMF_0346 | DvMF_0347 | DvMF_0346 | TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: dde:Dde_1990 SSU ribosomal protein S18P alanine acetyltransferase. | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | 0.582 |
| DvMF_0347 | tpiA | DvMF_0347 | DvMF_0348 | TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: dde:Dde_1990 SSU ribosomal protein S18P alanine acetyltransferase. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.531 |
| DvMF_2185 | DvMF_0125 | DvMF_2185 | DvMF_0125 | PFAM: ThiJ/PfpI domain protein; KEGG: bbr:BB3066 hypothetical protein. | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.502 |
| DvMF_2185 | DvMF_0346 | DvMF_2185 | DvMF_0346 | PFAM: ThiJ/PfpI domain protein; KEGG: bbr:BB3066 hypothetical protein. | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | 0.499 |
| DvMF_2291 | DvMF_0346 | DvMF_2291 | DvMF_0346 | PFAM: phosphoesterase PA-phosphatase related; KEGG: dde:Dde_0373 phosphoesterase, PA-phosphatase related. | PFAM: NUDIX hydrolase; KEGG: dde:Dde_1991 isopentenyl-diphosphate delta-isomerase. | 0.480 |
| ispDF | DvMF_0125 | DvMF_0257 | DvMF_0125 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_2201 farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.556 |