| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0513 | phnX | DvMF_0513 | DvMF_0514 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: bce:BC4053 GntR family transcriptional regulator. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.593 |
| DvMF_0543 | phnX | DvMF_0543 | DvMF_0514 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: amu:Amuc_0711 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.460 |
| DvMF_0816 | DvMF_1696 | DvMF_0816 | DvMF_1696 | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dde:Dde_1542 acetyl-CoA carboxylase. | PFAM: Phosphoglycerate mutase; 6-phosphofructo-2-kinase; KEGG: dde:Dde_0511 6-phosphofructo-2-kinase. | 0.535 |
| DvMF_0816 | guaA | DvMF_0816 | DvMF_3125 | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dde:Dde_1542 acetyl-CoA carboxylase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.471 |
| DvMF_0816 | phnX | DvMF_0816 | DvMF_0514 | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dde:Dde_1542 acetyl-CoA carboxylase. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.504 |
| DvMF_1696 | DvMF_0816 | DvMF_1696 | DvMF_0816 | PFAM: Phosphoglycerate mutase; 6-phosphofructo-2-kinase; KEGG: dde:Dde_0511 6-phosphofructo-2-kinase. | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dde:Dde_1542 acetyl-CoA carboxylase. | 0.535 |
| DvMF_1696 | phnX | DvMF_1696 | DvMF_0514 | PFAM: Phosphoglycerate mutase; 6-phosphofructo-2-kinase; KEGG: dde:Dde_0511 6-phosphofructo-2-kinase. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.628 |
| DvMF_2673 | guaA | DvMF_2673 | DvMF_3125 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: dde:Dde_2945 phosphomannomutase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.478 |
| DvMF_2673 | phnX | DvMF_2673 | DvMF_0514 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: dde:Dde_2945 phosphomannomutase. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.441 |
| DvMF_2809 | phnX | DvMF_2809 | DvMF_0514 | PFAM: aminotransferase class V; KEGG: dde:Dde_2744 aminotransferase, class V. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.710 |
| glmM | guaA | DvMF_0059 | DvMF_3125 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.478 |
| glmM | phnX | DvMF_0059 | DvMF_0514 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.441 |
| glpK | guaA | DvMF_0809 | DvMF_3125 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.431 |
| glpK | nadE | DvMF_0809 | DvMF_0449 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.498 |
| glpK | phnX | DvMF_0809 | DvMF_0514 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. | 0.481 |
| guaA | DvMF_0816 | DvMF_3125 | DvMF_0816 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | PFAM: acetyl-CoA carboxylase alpha subunit; KEGG: dde:Dde_1542 acetyl-CoA carboxylase. | 0.471 |
| guaA | DvMF_2673 | DvMF_3125 | DvMF_2673 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: dde:Dde_2945 phosphomannomutase. | 0.478 |
| guaA | glmM | DvMF_3125 | DvMF_0059 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.478 |
| guaA | glpK | DvMF_3125 | DvMF_0809 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.431 |
| guaA | nadE | DvMF_3125 | DvMF_0449 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.717 |