Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
DvMF_0771TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: dde:Dde_1581 DNA processing protein DprA, putative. (553 aa)    
Predicted Functional Partners:
DvMF_2857
PFAM: phosphoribosyltransferase; KEGG: lip:LI1111 predicted amidophosphoribosyltransferases.
 
 
 0.937
DvMF_2450
PFAM: ComEC/Rec2-related protein; KEGG: dde:Dde_0547 ComEC/Rec2-related protein.
 
  
 0.857
DvMF_2719
KEGG: dde:Dde_2808 competence protein ComM, putative.
 
 0.843
DvMF_2728
PFAM: magnesium chelatase ChlI subunit; KEGG: dde:Dde_2773 competence protein ComM, putative.
 
 
 0.842
DvMF_1037
Peptidase A24A domain protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.831
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.750
DvMF_3086
PFAM: DNA repair protein RadC; KEGG: dde:Dde_2442 DNA repair protein RadC; Belongs to the UPF0758 family.
  
  
 0.746
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.725
DvMF_0813
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: dde:Dde_1545 single-strand binding protein.
 
  
 0.711
DvMF_0769
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; KEGG: dde:Dde_1583 putative signal transduction protein.
       0.700
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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