Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_0798TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: dde:Dde_1557 thiamine biosynthesis protein ThiF. (206 aa)    
Predicted Functional Partners:
DvMF_0801
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: dde:Dde_1554 thiamine biosynthesis protein ThiS.
 
 0.996
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.966
DvMF_0799
TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: dde:Dde_1556 thiamine biosynthesis protein ThiH.
 
  
 0.931
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.930
DvMF_2331
KEGG: dde:Dde_3610 hypothetical protein.
     
  0.900
DvMF_1955
PFAM: thiamineS protein; KEGG: dde:Dde_2458 hypothetical protein.
  
 0.888
DvMF_1954
KEGG: pth:PTH_1468 hypothetical protein.
  
 0.839
DvMF_0872
KEGG: dde:Dde_2352 hypothetical protein.
  
 0.806
DvMF_2659
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
   
 0.779
DvMF_0207
PFAM: thiamine biosynthesis protein ThiC; KEGG: dde:Dde_1680 thiamine biosynthesis protein ThiC.
  
  
 0.723
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: low (20%) [HD]