| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0050 | DvMF_0844 | DvMF_0050 | DvMF_0844 | PFAM: RNP-1 like RNA-binding protein; KEGG: nis:NIS_0278 RNA-binding protein RNP-1. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | 0.500 |
| DvMF_0050 | glyA | DvMF_0050 | DvMF_3097 | PFAM: RNP-1 like RNA-binding protein; KEGG: nis:NIS_0278 RNA-binding protein RNP-1. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.540 |
| DvMF_0050 | polA | DvMF_0050 | DvMF_1713 | PFAM: RNP-1 like RNA-binding protein; KEGG: nis:NIS_0278 RNA-binding protein RNP-1. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.442 |
| DvMF_0844 | DvMF_0050 | DvMF_0844 | DvMF_0050 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | PFAM: RNP-1 like RNA-binding protein; KEGG: nis:NIS_0278 RNA-binding protein RNP-1. | 0.500 |
| DvMF_0844 | DvMF_1562 | DvMF_0844 | DvMF_1562 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: lip:LI0429 coproporphyrinogen III oxidase and related Fe-S oxidoreductases. | 0.570 |
| DvMF_0844 | DvMF_2490 | DvMF_0844 | DvMF_2490 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_3189 trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.508 |
| DvMF_0844 | glyA | DvMF_0844 | DvMF_3097 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.764 |
| DvMF_0844 | polA | DvMF_0844 | DvMF_1713 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.544 |
| DvMF_0844 | prmC | DvMF_0844 | DvMF_1445 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.659 |
| DvMF_0844 | rlmH | DvMF_0844 | DvMF_0845 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.649 |
| DvMF_0844 | rpoZ | DvMF_0844 | DvMF_2294 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.505 |
| DvMF_0844 | rsmA | DvMF_0844 | DvMF_0501 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.565 |
| DvMF_0844 | tsaD | DvMF_0844 | DvMF_0403 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.752 |
| DvMF_1562 | DvMF_0844 | DvMF_1562 | DvMF_0844 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: lip:LI0429 coproporphyrinogen III oxidase and related Fe-S oxidoreductases. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | 0.570 |
| DvMF_1562 | rsmA | DvMF_1562 | DvMF_0501 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: lip:LI0429 coproporphyrinogen III oxidase and related Fe-S oxidoreductases. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.516 |
| DvMF_2490 | DvMF_0844 | DvMF_2490 | DvMF_0844 | PFAM: Polyprenyl synthetase; KEGG: dde:Dde_3189 trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | 0.508 |
| glyA | DvMF_0050 | DvMF_3097 | DvMF_0050 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | PFAM: RNP-1 like RNA-binding protein; KEGG: nis:NIS_0278 RNA-binding protein RNP-1. | 0.540 |
| glyA | DvMF_0844 | DvMF_3097 | DvMF_0844 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: dde:Dde_2289 translation factor SUA5; Belongs to the SUA5 family. | 0.764 |
| glyA | polA | DvMF_3097 | DvMF_1713 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.638 |
| polA | DvMF_0050 | DvMF_1713 | DvMF_0050 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | PFAM: RNP-1 like RNA-binding protein; KEGG: nis:NIS_0278 RNA-binding protein RNP-1. | 0.442 |