| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0887 | mnmE | DvMF_0887 | DvMF_0886 | PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: dde:Dde_2393 single-stranded nucleic acid binding R3H. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.594 |
| DvMF_0887 | rnpA | DvMF_0887 | DvMF_0890 | PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: dde:Dde_2393 single-stranded nucleic acid binding R3H. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.836 |
| DvMF_0887 | rsmG | DvMF_0887 | DvMF_0848 | PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: dde:Dde_2393 single-stranded nucleic acid binding R3H. | Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.706 |
| DvMF_0887 | yidC | DvMF_0887 | DvMF_0888 | PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: dde:Dde_2393 single-stranded nucleic acid binding R3H. | 60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.899 |
| DvMF_2045 | DvMF_2047 | DvMF_2045 | DvMF_2047 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: dde:Dde_0029 chromosome segregation DNA-binding protein; Belongs to the ParB family. | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dde:Dde_0031 chromosome segregation ATPase. | 0.969 |
| DvMF_2045 | mnmE | DvMF_2045 | DvMF_0886 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: dde:Dde_0029 chromosome segregation DNA-binding protein; Belongs to the ParB family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.652 |
| DvMF_2045 | rsmG | DvMF_2045 | DvMF_0848 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: dde:Dde_0029 chromosome segregation DNA-binding protein; Belongs to the ParB family. | Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.721 |
| DvMF_2047 | DvMF_2045 | DvMF_2047 | DvMF_2045 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dde:Dde_0031 chromosome segregation ATPase. | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: dde:Dde_0029 chromosome segregation DNA-binding protein; Belongs to the ParB family. | 0.969 |
| DvMF_2047 | DvMF_2726 | DvMF_2047 | DvMF_2726 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dde:Dde_0031 chromosome segregation ATPase. | SMART: ParB domain protein nuclease; KEGG: azc:AZC_1530 hypothetical protein. | 0.812 |
| DvMF_2047 | rsmG | DvMF_2047 | DvMF_0848 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dde:Dde_0031 chromosome segregation ATPase. | Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.580 |
| DvMF_2726 | DvMF_2047 | DvMF_2726 | DvMF_2047 | SMART: ParB domain protein nuclease; KEGG: azc:AZC_1530 hypothetical protein. | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dde:Dde_0031 chromosome segregation ATPase. | 0.812 |
| DvMF_2726 | rsmG | DvMF_2726 | DvMF_0848 | SMART: ParB domain protein nuclease; KEGG: azc:AZC_1530 hypothetical protein. | Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.702 |
| gyrA | metG | DvMF_2084 | DvMF_0759 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.830 |
| gyrA | mnmG | DvMF_2084 | DvMF_0551 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.446 |
| gyrA | rnpA | DvMF_2084 | DvMF_0890 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.470 |
| gyrA | rsmG | DvMF_2084 | DvMF_0848 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.583 |
| gyrA | yidC | DvMF_2084 | DvMF_0888 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.477 |
| metG | gyrA | DvMF_0759 | DvMF_2084 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.830 |
| metG | mnmG | DvMF_0759 | DvMF_0551 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.553 |
| metG | rsmG | DvMF_0759 | DvMF_0848 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.581 |