STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnDUTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (967 aa)    
Predicted Functional Partners:
DvMF_0865
PFAM: nitrogen regulatory protein P-II; KEGG: dde:Dde_2310 nitrogen regulatory protein P-II (GlnB, GlnK); Belongs to the P(II) protein family.
 
 
 0.989
DvMF_3024
PFAM: nitrogen regulatory protein P-II; KEGG: sul:SYO3AOP1_0047 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.976
DvMF_2615
PFAM: nitrogen regulatory protein P-II; KEGG: pvi:Cvib_1345 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 
 0.695
DvMF_2614
PFAM: nitrogen regulatory protein P-II; KEGG: sfu:Sfum_1018 nitrogen regulatory protein P-II.
 
 
 
 0.650
DvMF_2660
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
     
 0.535
DvMF_0866
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: dde:Dde_2311 ammonium transporter.
     
 0.534
DvMF_2389
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; glutamate synthase alpha subunit domain protein; KEGG: sfu:Sfum_1723 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
   
 0.534
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.453
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
  
 0.452
DvMF_1089
KEGG: dde:Dde_1071 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
   
 
 0.449
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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