STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_0878PFAM: protein of unknown function UPF0052 and CofD; KEGG: sit:TM1040_2627 protein of unknown function UPF0052 and CofD. (473 aa)    
Predicted Functional Partners:
DvMF_0424
Conserved hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.836
DvMF_0879
Hypothetical protein.
       0.773
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.596
DvMF_1183
KEGG: dde:Dde_0979 hypothetical protein.
  
    0.563
DvMF_0342
KEGG: dde:Dde_1995 hypothetical protein.
  
     0.529
DvMF_0880
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
       0.503
DvMF_0851
PFAM: Sporulation domain protein; KEGG: lip:LI0230 hypothetical protein.
 
     0.461
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.