STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_0919KEGG: dde:Dde_2592 hypothetical protein. (178 aa)    
Predicted Functional Partners:
DvMF_0918
KEGG: dde:Dde_2591 hypothetical protein.
 
   0.986
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.802
DvMF_2025
KEGG: dde:Dde_0121 hypothetical protein.
  
     0.756
DvMF_2891
KEGG: dde:Dde_1106 5-enolpyruvylshikimate-3-phosphate synthase-like.
 
     0.719
DvMF_2961
KEGG: dde:Dde_1345 hypothetical protein.
  
     0.713
DvMF_2836
KEGG: dde:Dde_1022 hypothetical protein.
  
     0.663
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
   0.662
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.649
DvMF_0549
KEGG: dde:Dde_1811 hypothetical protein.
  
     0.647
DvMF_0472
KEGG: dde:Dde_2111 hypothetical protein.
  
     0.641
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.