| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0476 | DvMF_1046 | DvMF_0476 | DvMF_1046 | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | 0.520 |
| DvMF_0476 | DvMF_1860 | DvMF_0476 | DvMF_1860 | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | 0.581 |
| DvMF_0476 | queA | DvMF_0476 | DvMF_2053 | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.410 |
| DvMF_0476 | queF | DvMF_0476 | DvMF_1347 | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.422 |
| DvMF_1046 | DvMF_0476 | DvMF_1046 | DvMF_0476 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 0.520 |
| DvMF_1046 | DvMF_1047 | DvMF_1046 | DvMF_1047 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | SMART: Rhodanese domain protein; KEGG: sfu:Sfum_0093 rhodanese domain protein. | 0.571 |
| DvMF_1046 | DvMF_1860 | DvMF_1046 | DvMF_1860 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | 0.533 |
| DvMF_1046 | queA | DvMF_1046 | DvMF_2053 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.527 |
| DvMF_1046 | queC | DvMF_1046 | DvMF_1125 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.427 |
| DvMF_1046 | queE | DvMF_1046 | DvMF_1124 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.400 |
| DvMF_1046 | queF | DvMF_1046 | DvMF_1347 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.448 |
| DvMF_1047 | DvMF_1046 | DvMF_1047 | DvMF_1046 | SMART: Rhodanese domain protein; KEGG: sfu:Sfum_0093 rhodanese domain protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | 0.571 |
| DvMF_1860 | DvMF_0476 | DvMF_1860 | DvMF_0476 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 0.581 |
| DvMF_1860 | DvMF_1046 | DvMF_1860 | DvMF_1046 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | 0.533 |
| queA | DvMF_0476 | DvMF_2053 | DvMF_0476 | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 0.410 |
| queA | DvMF_1046 | DvMF_2053 | DvMF_1046 | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | 0.527 |
| queA | queC | DvMF_2053 | DvMF_1125 | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.488 |
| queA | queE | DvMF_2053 | DvMF_1124 | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.447 |
| queA | queF | DvMF_2053 | DvMF_1347 | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.562 |
| queC | DvMF_1046 | DvMF_1125 | DvMF_1046 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: afu:AF2409 iron-sulfur cluster binding protein. | 0.427 |