| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0129 | DvMF_1123 | DvMF_0129 | DvMF_1123 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.917 |
| DvMF_0129 | guaA | DvMF_0129 | DvMF_3125 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.496 |
| DvMF_0129 | queC | DvMF_0129 | DvMF_1125 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.854 |
| DvMF_0129 | queE | DvMF_0129 | DvMF_1124 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.982 |
| DvMF_0129 | queF | DvMF_0129 | DvMF_1347 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.764 |
| DvMF_1123 | DvMF_0129 | DvMF_1123 | DvMF_0129 | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | 0.917 |
| DvMF_1123 | guaA | DvMF_1123 | DvMF_3125 | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.496 |
| DvMF_1123 | queC | DvMF_1123 | DvMF_1125 | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.941 |
| DvMF_1123 | queE | DvMF_1123 | DvMF_1124 | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.992 |
| DvMF_1123 | queF | DvMF_1123 | DvMF_1347 | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.761 |
| DvMF_1473 | DvMF_1819 | DvMF_1473 | DvMF_1819 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dde:Dde_3016 anaerobic ribonucleoside triphosphate reductase. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dde:Dde_0277 anaerobic ribonucleoside triphosphate reductase. | 0.901 |
| DvMF_1473 | queE | DvMF_1473 | DvMF_1124 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dde:Dde_3016 anaerobic ribonucleoside triphosphate reductase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.830 |
| DvMF_1644 | guaA | DvMF_1644 | DvMF_3125 | KEGG: pfl:PFL_3748 hypothetical protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.403 |
| DvMF_1644 | purF | DvMF_1644 | DvMF_2307 | KEGG: pfl:PFL_3748 hypothetical protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.516 |
| DvMF_1644 | queC | DvMF_1644 | DvMF_1125 | KEGG: pfl:PFL_3748 hypothetical protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.530 |
| DvMF_1644 | queE | DvMF_1644 | DvMF_1124 | KEGG: pfl:PFL_3748 hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.489 |
| DvMF_1819 | DvMF_1473 | DvMF_1819 | DvMF_1473 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dde:Dde_0277 anaerobic ribonucleoside triphosphate reductase. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dde:Dde_3016 anaerobic ribonucleoside triphosphate reductase. | 0.901 |
| DvMF_1819 | queE | DvMF_1819 | DvMF_1124 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dde:Dde_0277 anaerobic ribonucleoside triphosphate reductase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.830 |
| guaA | DvMF_0129 | DvMF_3125 | DvMF_0129 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase, putative. | 0.496 |
| guaA | DvMF_1123 | DvMF_3125 | DvMF_1123 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: mxa:MXAN_6868 putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.496 |