STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_1193PFAM: protein of unknown function DUF6 transmembrane; KEGG: dde:Dde_0791 hypothetical protein. (334 aa)    
Predicted Functional Partners:
DvMF_1192
Hypothetical protein.
       0.639
DvMF_2178
TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: asa:ASA_3792 chaperone CsaA.
  
   0.507
DvMF_0436
KEGG: dde:Dde_1759 hypothetical protein.
  
     0.502
DvMF_2642
KEGG: dde:Dde_3102 hypothetical protein.
  
    0.448
DvMF_0857
PFAM: Cupin 2 conserved barrel domain protein; KEGG: dde:Dde_2303 hypothetical protein.
 
  
 0.438
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
       0.422
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.421
DvMF_2667
KEGG: dde:Dde_2939 hypothetical protein.
  
    0.419
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.