Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DvMF_1193PFAM: protein of unknown function DUF6 transmembrane; KEGG: dde:Dde_0791 hypothetical protein. (334 aa)    
Predicted Functional Partners:
DvMF_1192
Hypothetical protein.
       0.639
DvMF_2918
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 
 0.578
DvMF_2156
PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; KEGG: sfu:Sfum_2391 ABC transporter related.
   
 0.565
DvMF_0436
KEGG: dde:Dde_1759 hypothetical protein.
  
     0.502
DvMF_2178
TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: asa:ASA_3792 chaperone CsaA.
  
   0.496
DvMF_2642
KEGG: dde:Dde_3102 hypothetical protein.
  
    0.457
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
    0.453
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
     
  0.449
DvMF_0857
PFAM: Cupin 2 conserved barrel domain protein; KEGG: dde:Dde_2303 hypothetical protein.
 
  
 0.435
DvMF_2667
KEGG: dde:Dde_2939 hypothetical protein.
  
    0.428
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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