Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (361 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
DvMF_1358
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.940
DvMF_1339
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: dde:Dde_1390 molybdopterin binding domain-containing protein.
 
  
 0.913
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.907
folE2
Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.900
DvMF_1797
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.896
DvMF_1232
KEGG: dde:Dde_0707 formate dehydrogenase accessory protein FdhD, putative.
 
  
 0.877
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
  
 0.820
DvMF_3078
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: dde:Dde_2453 nucleoside triphosphate pyrophosphohydrolase.
    
 0.817
DvMF_0460
PFAM: adenylate cyclase; KEGG: dde:Dde_2101 adenylate cyclase.
    
  0.813
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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