Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DvMF_1361Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: dde:Dde_0878 periplasmic sensor signal transduction histidine kinase. (912 aa)    
Predicted Functional Partners:
DvMF_1360
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: dde:Dde_0879 two component Fis family transcriptional regulator.
 
 
 0.855
DvMF_2755
PFAM: response regulator receiver; KEGG: dde:Dde_2769 multi-sensor hybrid histidine kinase.
 
 
 0.690
DvMF_1550
KEGG: dde:Dde_0521 hypothetical protein.
  
     0.608
DvMF_0972
KEGG: dde:Dde_2610 hypothetical protein.
  
     0.551
DvMF_0902
Hypothetical protein.
  
     0.540
DvMF_1772
PFAM: response regulator receiver; KEGG: sfu:Sfum_0654 response regulator receiver protein.
 
 
 0.535
DvMF_2188
PFAM: response regulator receiver; KEGG: dde:Dde_0603 response regulator receiver domain-containing protein.
 
 
   0.531
DvMF_1858
KEGG: dde:Dde_3233 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.515
DvMF_1363
PFAM: conserved hypothetical protein; KEGG: dde:Dde_0876 hypothetical protein.
 
     0.478
DvMF_1223
Anti-sigma-factor antagonist; PFAM: response regulator receiver; Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dde:Dde_0710 response regulator receiver domain-containing protein.
  
 
   0.468
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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