| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0641 | DvMF_1424 | DvMF_0641 | DvMF_1424 | PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: dde:Dde_3539 aldehyde dehydrogenase, molybdenum-binding subunit apoprotein. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | 0.467 |
| DvMF_0641 | DvMF_2389 | DvMF_0641 | DvMF_2389 | PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: dde:Dde_3539 aldehyde dehydrogenase, molybdenum-binding subunit apoprotein. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; glutamate synthase alpha subunit domain protein; KEGG: sfu:Sfum_1723 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.639 |
| DvMF_0641 | pyrC | DvMF_0641 | DvMF_1426 | PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: dde:Dde_3539 aldehyde dehydrogenase, molybdenum-binding subunit apoprotein. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.599 |
| DvMF_1424 | DvMF_0641 | DvMF_1424 | DvMF_0641 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: dde:Dde_3539 aldehyde dehydrogenase, molybdenum-binding subunit apoprotein. | 0.467 |
| DvMF_1424 | DvMF_1749 | DvMF_1424 | DvMF_1749 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: dde:Dde_3487 prephenate dehydratase. | 0.437 |
| DvMF_1424 | DvMF_2389 | DvMF_1424 | DvMF_2389 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; glutamate synthase alpha subunit domain protein; KEGG: sfu:Sfum_1723 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.452 |
| DvMF_1424 | carB | DvMF_1424 | DvMF_2306 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.529 |
| DvMF_1424 | mqnA | DvMF_1424 | DvMF_1190 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.433 |
| DvMF_1424 | mqnB | DvMF_1424 | DvMF_2491 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | Purine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.936 |
| DvMF_1424 | mqnC | DvMF_1424 | DvMF_1189 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.412 |
| DvMF_1424 | mqnE | DvMF_1424 | DvMF_1188 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.936 |
| DvMF_1424 | pyrB | DvMF_1424 | DvMF_1425 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | KEGG: dde:Dde_2964 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.823 |
| DvMF_1424 | pyrC | DvMF_1424 | DvMF_1426 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.809 |
| DvMF_1749 | DvMF_1424 | DvMF_1749 | DvMF_1424 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: dde:Dde_3487 prephenate dehydratase. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | 0.437 |
| DvMF_1749 | carB | DvMF_1749 | DvMF_2306 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: dde:Dde_3487 prephenate dehydratase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.527 |
| DvMF_1749 | mqnA | DvMF_1749 | DvMF_1190 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: dde:Dde_3487 prephenate dehydratase. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.811 |
| DvMF_2389 | DvMF_0641 | DvMF_2389 | DvMF_0641 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; glutamate synthase alpha subunit domain protein; KEGG: sfu:Sfum_1723 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: dde:Dde_3539 aldehyde dehydrogenase, molybdenum-binding subunit apoprotein. | 0.639 |
| DvMF_2389 | DvMF_1424 | DvMF_2389 | DvMF_1424 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; glutamate synthase alpha subunit domain protein; KEGG: sfu:Sfum_1723 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | 0.452 |
| DvMF_2389 | carB | DvMF_2389 | DvMF_2306 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; glutamate synthase alpha subunit domain protein; KEGG: sfu:Sfum_1723 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.622 |
| carB | DvMF_1424 | DvMF_2306 | DvMF_1424 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: dde:Dde_2963 amidohydrolase family protein. | 0.529 |