Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DvMF_1461Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: dde:Dde_3003 two component Fis family transcriptional regulator. (491 aa)    
Predicted Functional Partners:
DvMF_1458
KEGG: dde:Dde_3000 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 0.971
DvMF_1460
KEGG: dde:Dde_3002 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; metal dependent phophohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; PAS fold-4 domain protein; Metal-dependent hydrolase HDOD; SMART: PAS domain containing protein; metal-dependent phosphohydrolase HD region.
  
 
 0.734
DvMF_0427
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.612
DvMF_1459
PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: dde:Dde_3001 hypothetical protein.
       0.585
DvMF_1089
KEGG: dde:Dde_1071 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.526
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
    0.516
DvMF_1457
KEGG: dde:Dde_2999 hypothetical protein.
       0.514
DvMF_1396
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: dde:Dde_2708 flagellar motor switch protein FliM.
  
  
 0.468
DvMF_0557
KEGG: dde:Dde_1800 flagellar synthesis regulator FleN, putative.
  
 
 0.432
DvMF_2012
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: dde:Dde_0382 flagellar synthesis regulator FleN.
  
 
 0.432
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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