Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_1565KEGG: dde:Dde_0512 hypothetical protein. (230 aa)    
Predicted Functional Partners:
DvMF_0382
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.639
DvMF_0880
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.639
DvMF_2718
KEGG: lip:LI0923 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family.
   
    0.638
DvMF_1459
PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: dde:Dde_3001 hypothetical protein.
   
    0.548
DvMF_0427
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
    0.543
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
    0.486
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
    0.486
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
   
    0.448
DvMF_2376
TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; ribonuclease E and G; KEGG: dde:Dde_0537 ribonuclease E.
   
    0.448
DvMF_0398
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: dde:Dde_1841 short chain dehydrogenase/reductase family oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.441
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.