STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_1749PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: dde:Dde_3487 prephenate dehydratase. (418 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.992
DvMF_2204
Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: dde:Dde_3596 L-aspartate aminotransferase.
 
 
 0.987
DvMF_1747
PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; KEGG: dde:Dde_3485 prephenate dehydrogenase.
  
 0.986
DvMF_1750
PFAM: 3-dehydroquinate synthase; KEGG: dde:Dde_3488 3-dehydroquinate synthase.
 
  
 0.985
DvMF_1746
PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: dde:Dde_3484 anthranilate synthase, component I.
 
 
 0.974
DvMF_1745
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: amu:Amuc_1532 anthranilate phosphoribosyltransferase.
  
 
 0.968
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: dde:Dde_1453 histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.962
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.959
DvMF_2889
PFAM: aminotransferase class I and II; KEGG: dde:Dde_1103 aspartate aminotransferase.
 
 
 0.936
kdsA
TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: dde:Dde_1766 2-dehydro-3-deoxyphosphooctonate aldolase.
 
  
 0.922
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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