Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DvMF_1763Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: ade:Adeh_2651 two component, sigma54 specific, transcriptional regulator, fis family. (388 aa)    
Predicted Functional Partners:
DvMF_0427
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.736
DvMF_1764
PFAM: protein of unknown function DUF81; KEGG: afu:AF1561 hypothetical protein.
       0.520
DvMF_1766
Sigma54 specific transcriptional regulator with PAS/PAC sensor, Fis family; KEGG: dde:Dde_0318 Fis family transcriptional regulator; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; PAS fold-4 domain protein; SMART: AAA ATPase.
 
    
0.484
DvMF_1765
KEGG: afu:AF1562 hypothetical protein.
       0.468
DvMF_1089
KEGG: dde:Dde_1071 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.458
DvMF_1396
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: dde:Dde_2708 flagellar motor switch protein FliM.
  
  
 0.454
DvMF_1768
PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfu:Sfum_0651 integral membrane sensor signal transduction histidine kinase.
   
 
 0.442
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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