Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DvMF_1766Sigma54 specific transcriptional regulator with PAS/PAC sensor, Fis family; KEGG: dde:Dde_0318 Fis family transcriptional regulator; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; PAS fold-4 domain protein; SMART: AAA ATPase. (567 aa)    
Predicted Functional Partners:
DvMF_1767
KEGG: dde:Dde_0319 hypothetical protein.
 
    0.839
DvMF_1768
PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfu:Sfum_0651 integral membrane sensor signal transduction histidine kinase.
     
 0.805
DvMF_1769
PFAM: response regulator receiver; KEGG: dde:Dde_0321 response regulator receiver domain-containing protein.
       0.786
DvMF_0427
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.781
DvMF_1765
KEGG: afu:AF1562 hypothetical protein.
       0.630
DvMF_1764
PFAM: protein of unknown function DUF81; KEGG: afu:AF1561 hypothetical protein.
  
    0.597
DvMF_1770
KEGG: sfu:Sfum_0655 hypothetical protein.
       0.570
aroA-2
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
   0.518
DvMF_1763
Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: ade:Adeh_2651 two component, sigma54 specific, transcriptional regulator, fis family.
 
    
0.484
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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