Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DvMF_1768PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfu:Sfum_0651 integral membrane sensor signal transduction histidine kinase. (576 aa)    
Predicted Functional Partners:
DvMF_1769
PFAM: response regulator receiver; KEGG: dde:Dde_0321 response regulator receiver domain-containing protein.
 
   0.964
DvMF_1767
KEGG: dde:Dde_0319 hypothetical protein.
 
    0.940
DvMF_2755
PFAM: response regulator receiver; KEGG: dde:Dde_2769 multi-sensor hybrid histidine kinase.
 
 
 0.907
DvMF_1772
PFAM: response regulator receiver; KEGG: sfu:Sfum_0654 response regulator receiver protein.
 
 
 0.845
DvMF_1766
Sigma54 specific transcriptional regulator with PAS/PAC sensor, Fis family; KEGG: dde:Dde_0318 Fis family transcriptional regulator; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; PAS fold-4 domain protein; SMART: AAA ATPase.
     
 0.805
DvMF_1988
PFAM: response regulator receiver; KEGG: sfu:Sfum_0648 response regulator receiver protein.
 
 
   0.787
DvMF_1096
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.775
DvMF_1492
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: lch:Lcho_4210 multi-sensor hybrid histidine kinase.
 
 
 0.751
DvMF_2452
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: dde:Dde_0544 periplasmic sensor hybrid histidine kinase.
 
 
0.714
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.710
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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