STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_1819TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dde:Dde_0277 anaerobic ribonucleoside triphosphate reductase. (636 aa)    
Predicted Functional Partners:
DvMF_1818
PFAM: Radical SAM domain protein; KEGG: dde:Dde_0278 radical SAM domain-containing protein.
 
  
 0.941
DvMF_3148
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    
 0.919
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.911
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.909
DvMF_1473
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dde:Dde_3016 anaerobic ribonucleoside triphosphate reductase.
  
  
 
0.901
DvMF_0460
PFAM: adenylate cyclase; KEGG: dde:Dde_2101 adenylate cyclase.
     
  0.900
DvMF_0787
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.900
DvMF_0965
KEGG: dde:Dde_1032 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: HpcH/HpaI aldolase; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
  0.900
DvMF_1407
PFAM: metal-dependent phosphohydrolase HD sub domain; CHASE2 domain protein; SMART: metal-dependent phosphohydrolase HD region; KEGG: dar:Daro_1897 metal-dependent phosphohydrolase.
     
  0.900
DvMF_3078
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: dde:Dde_2453 nucleoside triphosphate pyrophosphohydrolase.
     
  0.900
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.