Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DvMF_1822PFAM: aminotransferase class I and II; KEGG: dde:Dde_0276 aminotransferase, classes I and II. (405 aa)    
Predicted Functional Partners:
DvMF_0476
PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: dde:Dde_2115 methionine synthase (B12-dependent).
     
 0.969
DvMF_0262
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dde:Dde_2146 iron-sulfur cluster-binding protein.
     
 0.952
DvMF_1464
PFAM: protein of unknown function DUF39; KEGG: dde:Dde_3007 hypothetical protein.
     
 0.952
DvMF_2658
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: dde:Dde_3080 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.941
DvMF_2204
Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: dde:Dde_3596 L-aspartate aminotransferase.
 
  
0.916
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.914
DvMF_2889
PFAM: aminotransferase class I and II; KEGG: dde:Dde_1103 aspartate aminotransferase.
 
  
0.914
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.900
DvMF_1879
PFAM: regulatory protein LuxR; KEGG: swo:Swol_1080 ATP-dependent transcriptional regulator-like protein.
    
   0.843
DvMF_1412
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: dde:Dde_2731 homoserine dehydrogenase.
    
 0.813
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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