STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_1889KEGG: dde:Dde_3700 hypothetical protein. (159 aa)    
Predicted Functional Partners:
DvMF_1888
PFAM: methyladenine glycosylase; KEGG: dde:Dde_3701 DNA-3-methyladenine glycosylase I.
       0.773
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.643
DvMF_2097
PFAM: NADPH-dependent FMN reductase; KEGG: mba:Mbar_A2580 iron-sulfur flavoprotein.
   
  
 0.599
DvMF_2856
PFAM: NADPH-dependent FMN reductase; KEGG: dde:Dde_0785 iron-sulfur flavoprotein, putative.
   
  
 0.599
DvMF_2979
PFAM: NADPH-dependent FMN reductase; KEGG: mbn:Mboo_0650 NADPH-dependent FMN reductase.
   
  
 0.599
DvMF_2802
PFAM: transport-associated; KEGG: dde:Dde_2000 transport-associated protein.
   
  
 0.435
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.