| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_1365 | DvMF_1929 | DvMF_1365 | DvMF_1929 | PFAM: peptidase M16 domain protein; Peptidase M16C associated domain protein; KEGG: dde:Dde_2677 PreP peptidase. | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | 0.571 |
| DvMF_1365 | sucD | DvMF_1365 | DvMF_0026 | PFAM: peptidase M16 domain protein; Peptidase M16C associated domain protein; KEGG: dde:Dde_2677 PreP peptidase. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.555 |
| DvMF_1468 | DvMF_1929 | DvMF_1468 | DvMF_1929 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | 0.531 |
| DvMF_1468 | adk | DvMF_1468 | DvMF_0293 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.956 |
| DvMF_1468 | carB | DvMF_1468 | DvMF_2306 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.946 |
| DvMF_1468 | sucD | DvMF_1468 | DvMF_0026 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.708 |
| DvMF_1860 | DvMF_1929 | DvMF_1860 | DvMF_1929 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | 0.540 |
| DvMF_1860 | sucD | DvMF_1860 | DvMF_0026 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.971 |
| DvMF_1860 | topA | DvMF_1860 | DvMF_2069 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.965 |
| DvMF_1928 | DvMF_1929 | DvMF_1928 | DvMF_1929 | PFAM: FAD dependent oxidoreductase; KEGG: dde:Dde_0216 UDP-galactopyranose mutase. | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | 0.712 |
| DvMF_1929 | DvMF_1365 | DvMF_1929 | DvMF_1365 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | PFAM: peptidase M16 domain protein; Peptidase M16C associated domain protein; KEGG: dde:Dde_2677 PreP peptidase. | 0.571 |
| DvMF_1929 | DvMF_1468 | DvMF_1929 | DvMF_1468 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.531 |
| DvMF_1929 | DvMF_1860 | DvMF_1929 | DvMF_1860 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | 0.540 |
| DvMF_1929 | DvMF_1928 | DvMF_1929 | DvMF_1928 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | PFAM: FAD dependent oxidoreductase; KEGG: dde:Dde_0216 UDP-galactopyranose mutase. | 0.712 |
| DvMF_1929 | DvMF_2511 | DvMF_1929 | DvMF_2511 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: dde:Dde_3164 DHH family protein. | 0.533 |
| DvMF_1929 | adk | DvMF_1929 | DvMF_0293 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.594 |
| DvMF_1929 | aroQ | DvMF_1929 | DvMF_0373 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.586 |
| DvMF_1929 | carB | DvMF_1929 | DvMF_2306 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.550 |
| DvMF_1929 | sucD | DvMF_1929 | DvMF_0026 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.538 |
| DvMF_1929 | topA | DvMF_1929 | DvMF_2069 | Peptidase M24; PFAM: creatinase; peptidase M24; KEGG: dde:Dde_0217 M24 family peptidase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.539 |