| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_2026 | fmt | DvMF_2026 | DvMF_2040 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.813 |
| DvMF_2026 | rlmE | DvMF_2026 | DvMF_3200 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.782 |
| DvMF_2026 | rlmN | DvMF_2026 | DvMF_1431 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.676 |
| DvMF_2026 | rplC | DvMF_2026 | DvMF_0079 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.682 |
| DvMF_2026 | rplJ | DvMF_2026 | DvMF_1453 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.778 |
| DvMF_2026 | rplM | DvMF_2026 | DvMF_0969 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.690 |
| DvMF_2026 | rplV | DvMF_2026 | DvMF_0084 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.688 |
| DvMF_2026 | rplW | DvMF_2026 | DvMF_0081 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.690 |
| DvMF_2026 | rplX | DvMF_2026 | DvMF_0090 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.691 |
| DvMF_2026 | rpmD | DvMF_2026 | DvMF_0097 | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | PFAM: ribosomal protein L30; KEGG: dde:Dde_2239 50S ribosomal protein L30. | 0.748 |
| fmt | DvMF_2026 | DvMF_2040 | DvMF_2026 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.813 |
| fmt | rlmN | DvMF_2040 | DvMF_1431 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.645 |
| fmt | rplC | DvMF_2040 | DvMF_0079 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.480 |
| rlmE | DvMF_2026 | DvMF_3200 | DvMF_2026 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | PFAM: Fmu (Sun) domain protein; KEGG: dde:Dde_0122 NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.782 |
| rlmE | rplC | DvMF_3200 | DvMF_0079 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.837 |
| rlmE | rplJ | DvMF_3200 | DvMF_1453 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.851 |
| rlmE | rplM | DvMF_3200 | DvMF_0969 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.809 |
| rlmE | rplV | DvMF_3200 | DvMF_0084 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.807 |
| rlmE | rplW | DvMF_3200 | DvMF_0081 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.810 |
| rlmE | rplX | DvMF_3200 | DvMF_0090 | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.824 |