Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DvMF_2068PFAM: peptidase M48 Ste24p; KEGG: dde:Dde_0107 putative lipoprotein. (320 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
    0.634
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.597
DvMF_3157
PFAM: Peptidase M23; KEGG: dde:Dde_1436 M24/M37 family peptidase.
 
 
   0.578
DvMF_2025
KEGG: dde:Dde_0121 hypothetical protein.
  
 
 0.486
DvMF_1051
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: dde:Dde_1288 TPR repeat-containing protein.
  
 
  0.468
DvMF_3127
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: dde:Dde_1473 TPR repeat-containing protein.
  
 
  0.468
DvMF_2664
SMART: PDZ/DHR/GLGF domain protein; KEGG: mag:amb4535 Zn-dependent protease with chaperone function.
  
 
 0.438
DvMF_2365
PFAM: outer membrane efflux protein; KEGG: dde:Dde_3627 outer membrane efflux protein.
  
  
 0.436
DvMF_1083
PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: dde:Dde_1168 TPR repeat-containing protein.
 
 
 
 0.432
DvMF_2308
KEGG: dde:Dde_0335 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily.
 
     0.420
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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