Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DvMF_2186PFAM: Dual specificity protein phosphatase; KEGG: dde:Dde_0605 protein tyrosine phosphatase / dual specificity protein phosphatase. (500 aa)    
Predicted Functional Partners:
DvMF_2187
PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: dde:Dde_0604 pyruvate,water dikinase.
 
     0.890
DvMF_2190
TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: dde:Dde_0601 phosphonate-binding periplasmic protein.
 
   
 0.793
DvMF_2188
PFAM: response regulator receiver; KEGG: dde:Dde_0603 response regulator receiver domain-containing protein.
 
   
 0.773
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
 0.752
DvMF_0004
PFAM: TPR repeat-containing protein; protein of unknown function DUF181; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: dde:Dde_2348 hypothetical protein.
 
 
 0.744
DvMF_2191
KEGG: dde:Dde_0600 hypothetical protein.
 
   
 0.710
DvMF_0358
PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; KEGG: dde:Dde_1972 CBS; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
   
 0.675
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
   
 
  0.672
DvMF_0413
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: dde:Dde_2078 CBS.
   
 0.671
DvMF_1585
PFAM: CBS domain containing protein; KEGG: dde:Dde_0765 CBS.
   
 0.671
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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