| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0524 | DvMF_2236 | DvMF_0524 | DvMF_2236 | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | 0.557 |
| DvMF_0524 | DvMF_3095 | DvMF_0524 | DvMF_3095 | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: dde:Dde_2434 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase. | 0.647 |
| DvMF_0524 | nadD | DvMF_0524 | DvMF_0613 | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.940 |
| DvMF_0524 | nadE | DvMF_0524 | DvMF_0449 | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.650 |
| DvMF_0524 | nnrE | DvMF_0524 | DvMF_0279 | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.424 |
| DvMF_2236 | DvMF_0524 | DvMF_2236 | DvMF_0524 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.557 |
| DvMF_2236 | DvMF_2562 | DvMF_2236 | DvMF_2562 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | PFAM: ThiJ/PfpI domain protein; KEGG: gur:Gura_3528 ThiJ/PfpI domain protein. | 0.527 |
| DvMF_2236 | DvMF_3095 | DvMF_2236 | DvMF_3095 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: dde:Dde_2434 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase. | 0.507 |
| DvMF_2236 | birA | DvMF_2236 | DvMF_1000 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.553 |
| DvMF_2236 | guaA | DvMF_2236 | DvMF_3125 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.597 |
| DvMF_2236 | katA | DvMF_2236 | DvMF_1242 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. | 0.529 |
| DvMF_2236 | nadD | DvMF_2236 | DvMF_0613 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.446 |
| DvMF_2236 | nadE | DvMF_2236 | DvMF_0449 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.673 |
| DvMF_2236 | nnrE | DvMF_2236 | DvMF_0279 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.643 |
| DvMF_2236 | rpsL | DvMF_2236 | DvMF_0075 | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.487 |
| DvMF_2562 | DvMF_2236 | DvMF_2562 | DvMF_2236 | PFAM: ThiJ/PfpI domain protein; KEGG: gur:Gura_3528 ThiJ/PfpI domain protein. | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | 0.527 |
| DvMF_3095 | DvMF_0524 | DvMF_3095 | DvMF_0524 | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: dde:Dde_2434 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase. | KEGG: dde:Dde_1831 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.647 |
| DvMF_3095 | DvMF_2236 | DvMF_3095 | DvMF_2236 | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: dde:Dde_2434 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase. | PFAM: isochorismatase hydrolase; KEGG: sfu:Sfum_3430 isochorismatase hydrolase. | 0.507 |
| DvMF_3095 | birA | DvMF_3095 | DvMF_1000 | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: dde:Dde_2434 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.676 |
| DvMF_3095 | guaA | DvMF_3095 | DvMF_3125 | TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: dde:Dde_2434 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.674 |