STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_2243PFAM: AMP-dependent synthetase and ligase; KEGG: dde:Dde_0193 AMP-binding enzyme family protein. (562 aa)    
Predicted Functional Partners:
DvMF_0256
PFAM: AMP-dependent synthetase and ligase; KEGG: dde:Dde_1725 long-chain-fatty-acid--CoA ligase.
 
 
0.936
DvMF_0506
PFAM: PGAP1 family protein; KEGG: dde:Dde_1837 acetyltransferase and hydrolase with the alpha/beta hydrolase fold-like.
   
 
 0.841
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.683
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.642
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.576
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
 
 0.557
DvMF_0192
ATP-dependent helicase HrpB; KEGG: mag:amb1260 HrpA-like helicase; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases.
  
 
   0.505
rpsK
Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
 
 0.476
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
 0.468
DvMF_0337
PFAM: phospholipid/glycerol acyltransferase; KEGG: dde:Dde_2001 phospholipid/glycerol acyltransferase.
 
   
 0.444
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.