Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_2390Arsenite-activated ATPase ArsA; Anion-transporting ATPase; Belongs to the arsA ATPase family. (579 aa)    
Predicted Functional Partners:
DvMF_2391
PFAM: Arsenical resistance operon trans-acting repressor ArsD; KEGG: swo:Swol_0937 arsenical resistance operon trans-acting repressor.
 
   
 0.937
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
    
 
 0.819
DvMF_0437
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: bph:Bphy_1097 magnesium-translocating P-type ATPase.
   
 0.668
DvMF_2992
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: rca:Rcas_0372 ATPase, P-type (transporting), HAD superfamily, subfamily IC.
   
 0.668
DvMF_2392
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; KEGG: psa:PST_0241 arsenic resistance transcriptional regulator.
 
   
 0.622
DvMF_1109
PFAM: sodium/calcium exchanger membrane region; KEGG: cak:Caul_2287 sodium/calcium exchanger membrane region.
   
   0.546
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
    
 
 0.541
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
   0.538
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.515
DvMF_0004
PFAM: TPR repeat-containing protein; protein of unknown function DUF181; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: dde:Dde_2348 hypothetical protein.
    
 0.423
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.