Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: dde:Dde_3180 glutamate-1-semialdehyde 2,1-aminomutase. (425 aa)    
Predicted Functional Partners:
DvMF_2902
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: dde:Dde_2576 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.993
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.990
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.945
DvMF_2767
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dde:Dde_2837 uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase.
 
  
 0.900
DvMF_0298
TIGRFAM: siroheme synthase; KEGG: dde:Dde_2023 precorrin-2 dehydrogenase.
   
 0.779
DvMF_1005
KEGG: dde:Dde_2659 acyl carrier protein, putative.
    
 0.741
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 0.741
DvMF_0849
PFAM: Acyl transferase; KEGG: dde:Dde_2294 [acyl-carrier-protein] S-malonyltransferase.
    
 0.671
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.649
DvMF_0256
PFAM: AMP-dependent synthetase and ligase; KEGG: dde:Dde_1725 long-chain-fatty-acid--CoA ligase.
  
 
 0.635
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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