Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (401 aa)    
Predicted Functional Partners:
fcl
NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.999
DvMF_2691
KEGG: dde:Dde_2931 mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein.
 
 
 0.981
DvMF_1831
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: tle:Tlet_2020 regulatory protein MarR.
  
  
 0.866
DvMF_2699
PFAM: glycosyl transferase family 11; KEGG: dde:Dde_2877 alpha-1,2-fucosyltransferase, putative.
 
   
 0.765
rplD
Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
      0.738
DvMF_0690
TIGRFAM: sugar transferase, PEP-CTERM system associated; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: dde:Dde_0829 sugar transferase involved in lipopolysaccharide synthesis-like.
  
  
 0.715
DvMF_1573
Undecaprenyl-phosphate galactose phosphotransferase, WbaP; KEGG: lip:LI0512 sugar transferases involved in lipopolysaccharide synthesis; TIGRFAM: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase.
  
  
 0.715
DvMF_2702
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ote:Oter_3246 ABC transporter related.
  
  
 0.669
DvMF_2698
TIGRFAM: methyltransferase FkbM family; KEGG: dde:Dde_2875 hypothetical protein.
 
     0.660
DvMF_2701
PFAM: ABC-2 type transporter; KEGG: dde:Dde_2896 ABC transporter permease.
  
  
 0.636
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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