STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_2767TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dde:Dde_2837 uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase. (503 aa)    
Predicted Functional Partners:
DvMF_0298
TIGRFAM: siroheme synthase; KEGG: dde:Dde_2023 precorrin-2 dehydrogenase.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
DvMF_2902
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: dde:Dde_2576 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.992
DvMF_1500
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: dde:Dde_3107 cobalt-factor II C20-methyltransferase.
 
 
 0.963
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.952
DvMF_0181
PFAM: phosphoadenosine phosphosulfate reductase; KEGG: dde:Dde_1789 phosphoadenylylsulfate reductase (thioredoxin).
 
  
 0.923
DvMF_0018
PFAM: adenylylsulfate kinase; KEGG: pfo:PflO1_5510 adenylylsulfate kinase.
 
  
 0.885
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: dde:Dde_3180 glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.881
DvMF_2660
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.868
DvMF_0297
PFAM: cytochrome c assembly protein; KEGG: dde:Dde_2024 cytochrome c assembly protein, putative.
  
    0.850
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.