STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_2784Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: dde:Dde_2822 response regulator receiver domain-containing protein. (358 aa)    
Predicted Functional Partners:
DvMF_1225
Signal transduction histidine kinase, LytS; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: dde:Dde_0160 ATP-binding region, ATPase-like.
 
 
 0.908
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.527
DvMF_0356
PFAM: Tetratricopeptide TPR_4; KEGG: dde:Dde_1975 hypothetical protein.
 
  
 0.507
DvMF_2783
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
       0.500
DvMF_1550
KEGG: dde:Dde_0521 hypothetical protein.
  
     0.491
DvMF_2755
PFAM: response regulator receiver; KEGG: dde:Dde_2769 multi-sensor hybrid histidine kinase.
     
 0.441
DvMF_2586
KEGG: dde:Dde_0639 hypothetical protein.
  
     0.422
DvMF_2868
PFAM: Transglycosylase-associated protein; KEGG: gme:Gmet_1208 transglycosylase-associated protein.
   
    0.420
DvMF_1219
KEGG: dde:Dde_0714 transposase, putative.
  
    0.419
DvMF_1621
Flagellar hook-associated protein 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
     0.413
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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