STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_2813PFAM: integrase family protein; TOBE domain protein; KEGG: dde:Dde_3517 molybdenum-pterin binding domain-containing protein. (362 aa)    
Predicted Functional Partners:
DvMF_2550
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; PAS fold-4 domain protein; KEGG: dde:Dde_3715 multi-sensor signal transduction histidine kinase.
 
  
 0.639
DvMF_2857
PFAM: phosphoribosyltransferase; KEGG: lip:LI1111 predicted amidophosphoribosyltransferases.
  
    0.622
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.586
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
    0.586
DvMF_1747
PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; KEGG: dde:Dde_3485 prephenate dehydrogenase.
  
    0.553
DvMF_2598
PFAM: cytochrome c class III; KEGG: dde:Dde_0653 high-molecular-weight cytochrome c.
  
  
 0.551
DvMF_2594
KEGG: dde:Dde_0649 hmc operon protein 5.
 
    0.499
DvMF_2593
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: dde:Dde_0648 hmc operon protein 6.
 
     0.495
DvMF_0941
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dde:Dde_1055 ATPase.
 
  
 0.494
DvMF_0247
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
   0.487
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.