node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DvMF_0458 | DvMF_0569 | DvMF_0458 | DvMF_0569 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | 0.774 |
DvMF_0458 | DvMF_2660 | DvMF_0458 | DvMF_2660 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.483 |
DvMF_0458 | DvMF_3042 | DvMF_0458 | DvMF_3042 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: dde:Dde_1302 heat shock protein DnaJ-like. | 0.750 |
DvMF_0458 | dnaJ | DvMF_0458 | DvMF_2295 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.805 |
DvMF_0458 | dnaK | DvMF_0458 | DvMF_2835 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.957 |
DvMF_0458 | groL | DvMF_0458 | DvMF_3064 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.702 |
DvMF_0458 | groS | DvMF_0458 | DvMF_3063 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.718 |
DvMF_0458 | grpE | DvMF_0458 | DvMF_1194 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.826 |
DvMF_0458 | htpG | DvMF_0458 | DvMF_1117 | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.742 |
DvMF_0569 | DvMF_0458 | DvMF_0569 | DvMF_0458 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.774 |
DvMF_0569 | DvMF_2660 | DvMF_0569 | DvMF_2660 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.447 |
DvMF_0569 | clpB | DvMF_0569 | DvMF_0567 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.857 |
DvMF_0569 | dnaK | DvMF_0569 | DvMF_2835 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.990 |
DvMF_0569 | groL | DvMF_0569 | DvMF_3064 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.801 |
DvMF_0569 | groS | DvMF_0569 | DvMF_3063 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.731 |
DvMF_0569 | grpE | DvMF_0569 | DvMF_1194 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.953 |
DvMF_0569 | htpG | DvMF_0569 | DvMF_1117 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.871 |
DvMF_2660 | DvMF_0458 | DvMF_2660 | DvMF_0458 | Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | KEGG: dde:Dde_2099 ATPase; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.483 |
DvMF_2660 | DvMF_0569 | DvMF_2660 | DvMF_0569 | Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: dde:Dde_1659 heat shock protein DnaJ-like. | 0.447 |
DvMF_2660 | DvMF_3042 | DvMF_2660 | DvMF_3042 | Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | PFAM: heat shock protein DnaJ domain protein; KEGG: dde:Dde_1302 heat shock protein DnaJ-like. | 0.447 |