Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nhaANa+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (460 aa)    
Predicted Functional Partners:
DvMF_2172
PFAM: DSBA oxidoreductase; KEGG: dde:Dde_0163 DsbA-like thioredoxin domain-containing protein.
 
    
 0.775
DvMF_0543
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: amu:Amuc_0711 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.582
DvMF_2660
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
     
 0.526
DvMF_1119
Sodium/hydrogen exchanger; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: dol:Dole_0855 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.495
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.424
DvMF_3140
PFAM: Citrate transporter; KEGG: dde:Dde_1483 hypothetical protein.
     
 0.413
DvMF_0379
PFAM: natural resistance-associated macrophage protein; KEGG: tpd:Teth39_1570 natural resistance-associated macrophage protein.
     
 0.404
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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