| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_1365 | DvMF_3039 | DvMF_1365 | DvMF_3039 | PFAM: peptidase M16 domain protein; Peptidase M16C associated domain protein; KEGG: dde:Dde_2677 PreP peptidase. | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | 0.571 |
| DvMF_1365 | sucD | DvMF_1365 | DvMF_0026 | PFAM: peptidase M16 domain protein; Peptidase M16C associated domain protein; KEGG: dde:Dde_2677 PreP peptidase. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.555 |
| DvMF_1468 | DvMF_3039 | DvMF_1468 | DvMF_3039 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | 0.531 |
| DvMF_1468 | adk | DvMF_1468 | DvMF_0293 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.956 |
| DvMF_1468 | carB | DvMF_1468 | DvMF_2306 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.946 |
| DvMF_1468 | guaB | DvMF_1468 | DvMF_3126 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.871 |
| DvMF_1468 | sucD | DvMF_1468 | DvMF_0026 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.708 |
| DvMF_1860 | DvMF_3039 | DvMF_1860 | DvMF_3039 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | 0.540 |
| DvMF_1860 | guaB | DvMF_1860 | DvMF_3126 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.920 |
| DvMF_1860 | sucD | DvMF_1860 | DvMF_0026 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.971 |
| DvMF_1860 | topA | DvMF_1860 | DvMF_2069 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.965 |
| DvMF_3038 | DvMF_3039 | DvMF_3038 | DvMF_3039 | PFAM: regulatory protein TetR; KEGG: gme:Gmet_0803 transcriptional regulator, TetR family. | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | 0.477 |
| DvMF_3039 | DvMF_1365 | DvMF_3039 | DvMF_1365 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | PFAM: peptidase M16 domain protein; Peptidase M16C associated domain protein; KEGG: dde:Dde_2677 PreP peptidase. | 0.571 |
| DvMF_3039 | DvMF_1468 | DvMF_3039 | DvMF_1468 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dde:Dde_3011 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.531 |
| DvMF_3039 | DvMF_1860 | DvMF_3039 | DvMF_1860 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | 0.540 |
| DvMF_3039 | DvMF_3038 | DvMF_3039 | DvMF_3038 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | PFAM: regulatory protein TetR; KEGG: gme:Gmet_0803 transcriptional regulator, TetR family. | 0.477 |
| DvMF_3039 | adk | DvMF_3039 | DvMF_0293 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.488 |
| DvMF_3039 | carB | DvMF_3039 | DvMF_2306 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: dde:Dde_0333 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.550 |
| DvMF_3039 | gatA | DvMF_3039 | DvMF_2838 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.514 |
| DvMF_3039 | guaB | DvMF_3039 | DvMF_3126 | PFAM: peptidase M24; KEGG: dde:Dde_1305 M24 family peptidase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.464 |