Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DvMF_3086PFAM: DNA repair protein RadC; KEGG: dde:Dde_2442 DNA repair protein RadC; Belongs to the UPF0758 family. (225 aa)    
Predicted Functional Partners:
DvMF_2587
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.837
DvMF_2821
PFAM: Rod shape-determining protein MreC; KEGG: dde:Dde_0995 rod shape-determining protein MreC.
  
  
 0.819
DvMF_2857
PFAM: phosphoribosyltransferase; KEGG: lip:LI1111 predicted amidophosphoribosyltransferases.
 
    0.763
DvMF_0771
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: dde:Dde_1581 DNA processing protein DprA, putative.
  
  
 0.746
DvMF_2450
PFAM: ComEC/Rec2-related protein; KEGG: dde:Dde_0547 ComEC/Rec2-related protein.
  
  
 0.727
DvMF_3088
KEGG: dde:Dde_2441 hypothetical protein.
     
 0.661
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.650
lon-2
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
 
     0.645
DvMF_3085
PFAM: acylphosphatase; KEGG: sru:SRU_2068 acylphosphatase.
       0.605
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.595
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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