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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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DvMF_3107PFAM: FxsA cytoplasmic membrane protein; KEGG: dde:Dde_2422 FxsA protein. (253 aa)    
Predicted Functional Partners:
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.733
DvMF_0654
PFAM: Amidohydrolase 3; KEGG: bpe:BP2617 hypothetical protein.
  
  
 0.716
htpX
PFAM: peptidase M48 Ste24p; KEGG: dde:Dde_1051 HtpX-2 peptidase; Belongs to the peptidase M48B family.
   
  
 0.615
hslU
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
  
 0.589
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.571
DvMF_3108
PFAM: Rhomboid family protein; KEGG: dde:Dde_2421 rhomboid family protein.
       0.526
DvMF_0402
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: dde:Dde_2067 thioredoxin; Belongs to the thioredoxin family.
   
    0.494
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
      
 0.486
DvMF_0311
PFAM: heat shock protein Hsp20; KEGG: dde:Dde_2008 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
   
    0.448
DvMF_2181
PFAM: heat shock protein Hsp20; KEGG: rca:Rcas_4342 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
   
    0.448
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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