STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_3107PFAM: FxsA cytoplasmic membrane protein; KEGG: dde:Dde_2422 FxsA protein. (253 aa)    
Predicted Functional Partners:
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.712
DvMF_0654
PFAM: Amidohydrolase 3; KEGG: bpe:BP2617 hypothetical protein.
  
    0.678
hslU
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
  
 0.588
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.544
htpX
PFAM: peptidase M48 Ste24p; KEGG: dde:Dde_1051 HtpX-2 peptidase; Belongs to the peptidase M48B family.
   
  
 0.538
DvMF_3108
PFAM: Rhomboid family protein; KEGG: dde:Dde_2421 rhomboid family protein.
       0.519
DvMF_0402
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: dde:Dde_2067 thioredoxin; Belongs to the thioredoxin family.
   
    0.491
DvMF_0311
PFAM: heat shock protein Hsp20; KEGG: dde:Dde_2008 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
   
    0.420
DvMF_2181
PFAM: heat shock protein Hsp20; KEGG: rca:Rcas_4342 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
   
    0.420
DvMF_2648
PFAM: heat shock protein Hsp20; KEGG: dde:Dde_3092 HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
   
    0.420
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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