Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hypBTIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: dde:Dde_1307 hydrogenase accessory protein HypB. (218 aa)    
Predicted Functional Partners:
DvMF_3166
PFAM: hydrogenase expression/synthesis HypA; KEGG: dde:Dde_1308 hydrogenase nickel insertion protein HypA, putative.
 
 0.995
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 0.979
hypD
PFAM: hydrogenase formation HypD protein; KEGG: dde:Dde_0364 hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.959
DvMF_0268
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: dde:Dde_2140 hydrogenase assembly chaperone HypC/HupF.
 
  
 0.914
hypE
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: dde:Dde_0363 hydrogenase expression/formation protein HypE.
 
  
 0.906
DvMF_2355
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: dde:Dde_0555 (NiFe) hydrogenase maturation protein HypF.
 
   
 0.887
DvMF_1013
PFAM: peptidylprolyl isomerase FKBP-type; KEGG: dde:Dde_2668 peptidyl-prolyl cis-trans isomerase, FKBP-type.
    
 
 0.753
DvMF_0273
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dde:Dde_2135 periplasmic (NiFeSe) hydrogenase, large subunit, selenocysteine-containing.
 
  
 0.655
hysA
KEGG: dde:Dde_2134 hydrogenase (NiFe) small subunit (HydA); TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
  
 0.545
DvMF_1732
KEGG: dde:Dde_3755 hydrogenase (NiFe) small subunit (HydA); TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
  
 0.530
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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