| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DvMF_0327 | DvMF_3173 | DvMF_0327 | DvMF_3173 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: dde:Dde_1213 hydrogenase, putative. | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | 0.461 |
| DvMF_0937 | DvMF_3173 | DvMF_0937 | DvMF_3173 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: dde:Dde_3636 ferredoxin--NADP(+) reductase subunit alpha. | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | 0.461 |
| DvMF_1337 | DvMF_3173 | DvMF_1337 | DvMF_3173 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | 0.986 |
| DvMF_1337 | mqnA | DvMF_1337 | DvMF_1190 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.834 |
| DvMF_1337 | mqnB | DvMF_1337 | DvMF_2491 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | Purine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.761 |
| DvMF_1337 | mqnC | DvMF_1337 | DvMF_1189 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.821 |
| DvMF_1337 | mqnD | DvMF_1337 | DvMF_1187 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.823 |
| DvMF_1337 | mqnE | DvMF_1337 | DvMF_1188 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.810 |
| DvMF_1337 | ubiX | DvMF_1337 | DvMF_2128 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.979 |
| DvMF_2142 | DvMF_3173 | DvMF_2142 | DvMF_3173 | KEGG: dde:Dde_0057 dihydroorotate oxidase B, electron transfer subunit. | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | 0.461 |
| DvMF_3173 | DvMF_0327 | DvMF_3173 | DvMF_0327 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: dde:Dde_1213 hydrogenase, putative. | 0.461 |
| DvMF_3173 | DvMF_0937 | DvMF_3173 | DvMF_0937 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: dde:Dde_3636 ferredoxin--NADP(+) reductase subunit alpha. | 0.461 |
| DvMF_3173 | DvMF_1337 | DvMF_3173 | DvMF_1337 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: dde:Dde_1392 4-hydroxybenzoate octaprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.986 |
| DvMF_3173 | DvMF_2142 | DvMF_3173 | DvMF_2142 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | KEGG: dde:Dde_0057 dihydroorotate oxidase B, electron transfer subunit. | 0.461 |
| DvMF_3173 | mqnA | DvMF_3173 | DvMF_1190 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.818 |
| DvMF_3173 | mqnB | DvMF_3173 | DvMF_2491 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | Purine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.715 |
| DvMF_3173 | mqnC | DvMF_3173 | DvMF_1189 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.783 |
| DvMF_3173 | mqnD | DvMF_3173 | DvMF_1187 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.791 |
| DvMF_3173 | mqnE | DvMF_3173 | DvMF_1188 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.770 |
| DvMF_3173 | ubiX | DvMF_3173 | DvMF_2128 | PFAM: Carboxylyase-related protein; KEGG: dde:Dde_1323 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.994 |