STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (128 aa)    
Predicted Functional Partners:
hypB
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: dde:Dde_1307 hydrogenase accessory protein HypB.
 
 
 0.941
DvMF_3187
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rru:Rru_A1426 4Fe-4S ferredoxin, iron-sulfur binding.
  
  
 0.916
hypD
PFAM: hydrogenase formation HypD protein; KEGG: dde:Dde_0364 hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.837
DvMF_0273
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dde:Dde_2135 periplasmic (NiFeSe) hydrogenase, large subunit, selenocysteine-containing.
 
 
 0.833
hypE
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: dde:Dde_0363 hydrogenase expression/formation protein HypE.
 
  
 0.823
DvMF_3189
NADH dehydrogenase (quinone); PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: chy:CHY_1827 carbon monoxide-induced hydrogenase, large subunit.
 
 
 0.813
DvMF_2355
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: dde:Dde_0555 (NiFe) hydrogenase maturation protein HypF.
 
   
 0.810
DvMF_1733
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dde:Dde_3756 periplasmic (NiFe) hydrogenase, large subunit, isozyme 2; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.789
hydB
Nickel-dependent hydrogenase large subunit; Catalyzes the reversible oxidoreduction of molecular hydrogen, in conjunction with a specific electron acceptor, cytochrome c3.
 
 
 0.787
DvMF_3192
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: rru:Rru_A1422 NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
  
 0.779
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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