node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EJZ85662.1 | EJZ85663.1 | HMPREF9241_01206 | HMPREF9241_01207 | Exodeoxyribonuclease III (xth). | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.675 |
EJZ85662.1 | EJZ86205.1 | HMPREF9241_01206 | HMPREF9241_00830 | Exodeoxyribonuclease III (xth). | Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. | 0.643 |
EJZ85662.1 | EJZ86911.1 | HMPREF9241_01206 | HMPREF9241_00500 | Exodeoxyribonuclease III (xth). | Hypothetical protein. | 0.899 |
EJZ85662.1 | EJZ87761.1 | HMPREF9241_01206 | HMPREF9241_00389 | Exodeoxyribonuclease III (xth). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.924 |
EJZ85662.1 | EJZ88186.1 | HMPREF9241_01206 | HMPREF9241_00047 | Exodeoxyribonuclease III (xth). | Exodeoxyribonuclease III (xth). | 0.912 |
EJZ85662.1 | folD | HMPREF9241_01206 | HMPREF9241_01209 | Exodeoxyribonuclease III (xth). | FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.542 |
EJZ85662.1 | glyA | HMPREF9241_01206 | HMPREF9241_01210 | Exodeoxyribonuclease III (xth). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.542 |
EJZ85662.1 | polA | HMPREF9241_01206 | HMPREF9241_00869 | Exodeoxyribonuclease III (xth). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.919 |
EJZ85662.1 | tadA | HMPREF9241_01206 | HMPREF9241_00496 | Exodeoxyribonuclease III (xth). | Hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.755 |
EJZ85662.1 | ung | HMPREF9241_01206 | HMPREF9241_00619 | Exodeoxyribonuclease III (xth). | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.841 |
EJZ85663.1 | EJZ85662.1 | HMPREF9241_01207 | HMPREF9241_01206 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Exodeoxyribonuclease III (xth). | 0.675 |
EJZ85663.1 | folD | HMPREF9241_01207 | HMPREF9241_01209 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.529 |
EJZ85663.1 | glyA | HMPREF9241_01207 | HMPREF9241_01210 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.530 |
EJZ86205.1 | EJZ85662.1 | HMPREF9241_00830 | HMPREF9241_01206 | Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. | Exodeoxyribonuclease III (xth). | 0.643 |
EJZ86205.1 | EJZ88186.1 | HMPREF9241_00830 | HMPREF9241_00047 | Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. | Exodeoxyribonuclease III (xth). | 0.643 |
EJZ86205.1 | polA | HMPREF9241_00830 | HMPREF9241_00869 | Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.428 |
EJZ86911.1 | EJZ85662.1 | HMPREF9241_00500 | HMPREF9241_01206 | Hypothetical protein. | Exodeoxyribonuclease III (xth). | 0.899 |
EJZ86911.1 | EJZ87761.1 | HMPREF9241_00500 | HMPREF9241_00389 | Hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.704 |
EJZ86911.1 | EJZ88186.1 | HMPREF9241_00500 | HMPREF9241_00047 | Hypothetical protein. | Exodeoxyribonuclease III (xth). | 0.899 |
EJZ86911.1 | polA | HMPREF9241_00500 | HMPREF9241_00869 | Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.472 |