STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKU93671.1Hypothetical protein. (252 aa)    
Predicted Functional Partners:
EKU93357.1
Hypothetical protein.
    
 
 0.802
EKU92843.1
Hypothetical protein.
    
 
 0.802
EKU93670.1
Hypothetical protein.
       0.783
EKU94384.1
Hypothetical protein; Essential cell division protein.
   
 
 0.719
EKU93672.1
tryptophan-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.522
EKU93536.1
Hypothetical protein; Belongs to the peptidase S8 family.
  
 
 0.503
EKU94176.1
Hypothetical protein.
  
  
 0.483
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.481
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.443
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.432
Your Current Organism:
Alloiococcus otitis
NCBI taxonomy Id: 883081
Other names: A. otitis ATCC 51267, Alloiococcus otitis ATCC 51267
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.