| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHO85280.1 | ftsY | HMPREF0380_01005 | HMPREF0380_01010 | Hypothetical protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.751 |
| EHO85280.1 | glyA | HMPREF0380_01005 | HMPREF0380_01006 | Hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.819 |
| EHO85280.1 | gpsA | HMPREF0380_01005 | HMPREF0380_01013 | Hypothetical protein. | Hypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.752 |
| EHO85280.1 | plsX | HMPREF0380_01005 | HMPREF0380_01007 | Hypothetical protein. | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.774 |
| EHO85280.1 | plsY | HMPREF0380_01005 | HMPREF0380_01012 | Hypothetical protein. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.752 |
| EHO85280.1 | rnc | HMPREF0380_01005 | HMPREF0380_01008 | Hypothetical protein. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.762 |
| EHO85280.1 | smc | HMPREF0380_01005 | HMPREF0380_01009 | Hypothetical protein. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.762 |
| EHO85935.1 | EHO85938.1 | HMPREF0380_00787 | HMPREF0380_00790 | Hypothetical protein; Belongs to the thiolase-like superfamily. FabH family. | Malonyl CoA-acyl carrier protein transacylase. | 0.999 |
| EHO85935.1 | glyA | HMPREF0380_00787 | HMPREF0380_01006 | Hypothetical protein; Belongs to the thiolase-like superfamily. FabH family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.407 |
| EHO85935.1 | plsX | HMPREF0380_00787 | HMPREF0380_01007 | Hypothetical protein; Belongs to the thiolase-like superfamily. FabH family. | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.934 |
| EHO85935.1 | rnc | HMPREF0380_00787 | HMPREF0380_01008 | Hypothetical protein; Belongs to the thiolase-like superfamily. FabH family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.408 |
| EHO85938.1 | EHO85935.1 | HMPREF0380_00790 | HMPREF0380_00787 | Malonyl CoA-acyl carrier protein transacylase. | Hypothetical protein; Belongs to the thiolase-like superfamily. FabH family. | 0.999 |
| EHO85938.1 | plsX | HMPREF0380_00790 | HMPREF0380_01007 | Malonyl CoA-acyl carrier protein transacylase. | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.941 |
| EHO85938.1 | rpsM | HMPREF0380_00790 | HMPREF0380_00460 | Malonyl CoA-acyl carrier protein transacylase. | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. | 0.499 |
| ftsY | EHO85280.1 | HMPREF0380_01010 | HMPREF0380_01005 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Hypothetical protein. | 0.751 |
| ftsY | glyA | HMPREF0380_01010 | HMPREF0380_01006 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.799 |
| ftsY | gpsA | HMPREF0380_01010 | HMPREF0380_01013 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Hypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.782 |
| ftsY | plsX | HMPREF0380_01010 | HMPREF0380_01007 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.801 |
| ftsY | plsY | HMPREF0380_01010 | HMPREF0380_01012 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.782 |
| ftsY | rnc | HMPREF0380_01010 | HMPREF0380_01008 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.880 |