node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHR34466.1 | EHR35706.1 | HMPREF9709_00773 | HMPREF9709_00397 | 1-acylglycerol-3-phosphate O-acyltransferase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.459 |
EHR34466.1 | EHR36070.1 | HMPREF9709_00773 | HMPREF9709_00166 | 1-acylglycerol-3-phosphate O-acyltransferase. | Glycerol kinase. | 0.780 |
EHR34466.1 | gpsA | HMPREF9709_00773 | HMPREF9709_00793 | 1-acylglycerol-3-phosphate O-acyltransferase. | Hypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.973 |
EHR34466.1 | ldh | HMPREF9709_00773 | HMPREF9709_00809 | 1-acylglycerol-3-phosphate O-acyltransferase. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.417 |
EHR34466.1 | plsX | HMPREF9709_00773 | HMPREF9709_00882 | 1-acylglycerol-3-phosphate O-acyltransferase. | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.795 |
EHR34466.1 | plsY | HMPREF9709_00773 | HMPREF9709_00794 | 1-acylglycerol-3-phosphate O-acyltransferase. | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.988 |
EHR34485.1 | EHR34493.1 | HMPREF9709_00792 | HMPREF9709_00800 | Hypothetical protein. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.717 |
EHR34485.1 | der | HMPREF9709_00792 | HMPREF9709_00795 | Hypothetical protein. | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.802 |
EHR34485.1 | glyA | HMPREF9709_00792 | HMPREF9709_00796 | Hypothetical protein. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.800 |
EHR34485.1 | gpsA | HMPREF9709_00792 | HMPREF9709_00793 | Hypothetical protein. | Hypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.802 |
EHR34485.1 | ldh | HMPREF9709_00792 | HMPREF9709_00809 | Hypothetical protein. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.410 |
EHR34485.1 | plsY | HMPREF9709_00792 | HMPREF9709_00794 | Hypothetical protein. | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.802 |
EHR34493.1 | EHR34485.1 | HMPREF9709_00800 | HMPREF9709_00792 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hypothetical protein. | 0.717 |
EHR34493.1 | EHR35706.1 | HMPREF9709_00800 | HMPREF9709_00397 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.975 |
EHR34493.1 | der | HMPREF9709_00800 | HMPREF9709_00795 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.834 |
EHR34493.1 | glyA | HMPREF9709_00800 | HMPREF9709_00796 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.907 |
EHR34493.1 | gpsA | HMPREF9709_00800 | HMPREF9709_00793 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hypothetical protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.792 |
EHR34493.1 | ldh | HMPREF9709_00800 | HMPREF9709_00809 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.842 |
EHR34493.1 | plsY | HMPREF9709_00800 | HMPREF9709_00794 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.896 |
EHR35706.1 | EHR34466.1 | HMPREF9709_00397 | HMPREF9709_00773 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 1-acylglycerol-3-phosphate O-acyltransferase. | 0.459 |