STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHR33900.1Hypothetical protein. (72 aa)    
Predicted Functional Partners:
EHR31816.1
Hypothetical protein.
   
 
 0.953
EHR31700.1
Hypothetical protein.
 
   
 0.817
EHR31699.1
Hypothetical protein.
 
     0.789
EHR33888.1
Putative phage replisome organizer.
 
     0.706
EHR33892.1
Hypothetical protein.
 
   
 0.694
EHR33890.1
Hypothetical protein.
  
     0.646
EHR33899.1
Hypothetical protein.
       0.592
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.551
EHR33898.1
Hypothetical protein.
       0.503
lysS
lysine-tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
     
 0.478
Your Current Organism:
Helcococcus kunzii
NCBI taxonomy Id: 883114
Other names: H. kunzii ATCC 51366, Helcococcus kunzii ATCC 51366
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.