STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHR33931.1DNA protecting protein DprA. (363 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.950
EHR34480.1
Mg chelatase-like protein.
 
 0.917
EHR33345.1
comF family protein.
 
 
 0.904
EHR35802.1
Hypothetical protein.
 
  
 0.899
EHR33932.1
TIGR00252 family protein; Belongs to the UPF0102 family.
 
    0.892
rnhB
Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.817
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.748
EHR33330.1
Hypothetical protein.
  
  
 0.706
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.657
EHR34685.1
DNA repair protein RadC; Belongs to the UPF0758 family.
  
  
 0.642
Your Current Organism:
Helcococcus kunzii
NCBI taxonomy Id: 883114
Other names: H. kunzii ATCC 51366, Helcococcus kunzii ATCC 51366
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.